Neuraminidase inhibitors improve outcome of patients with leukemia and influenza: An observational study

被引:39
作者
Chemaly, Roy F.
Torres, Harrys A.
Aguilera, Elizabeth A.
Mattiuzzi, Gloria
Cabanillas, Maria
Kantarjian, Hagop
Gonzalez, Virginia
Safdar, Amar
Raad, Issam I.
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Infect Dis, Infect Control & Employee Hlth Unit 402, Houston, TX 77230 USA
[2] Univ Texas, MD Anderson Canc Ctr, Dept Infect Control, Houston, TX 77230 USA
[3] Univ Texas, MD Anderson Canc Ctr, Dept Employee Hlth, Houston, TX 77230 USA
[4] Univ Texas, MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77230 USA
关键词
D O I
10.1086/512374
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We reviewed the records of 33 patients with leukemia who experienced influenza during the period from October 2000 to March 2004. Three (38%) of the 8 patients who did not receive neuraminidase inhibitor therapy and none of the 25 patients who received it died of influenza pneumonia (P = .001). The use of neuraminidase inhibitor therapy seems improve the outcome of influenza in patients with leukemia.
引用
收藏
页码:964 / 967
页数:4
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