Adipokines and adipocyte targets in the future management of obesity and the metabolic syndrome

被引：50

作者：

Kralisch, S. ^{[1
]}

Bluher, M. ^{[1
]}

Paschke, R. ^{[1
]}

Stumvoll, M. ^{[1
]}

Fasshauer, M. ^{[1
]}

机构：

[1] Univ Leipzig, Dept Internal Med 3, D-04103 Leipzig, Germany

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 01期

关键词：

adipokine; diabetes mellitus; insulin resistance; obesity;

D O I：

10.2174/138955707779317821

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulin-sensitizers/insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.

引用

页码：39 / 45

页数：7

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