Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery

被引：55

作者：

Boughey, Judy C. ^{[1
]}

Goravanchi, Farzin ^{[2
]}

Parris, Ronald N. ^{[2
]}

Kee, Spencer S. ^{[2
]}

Kowalski, Alicia M. ^{[2
]}

Frenzel, John C. ^{[2
]}

Bedrosian, Isabelle ^{[1
]}

Meric-Bernstam, Funda ^{[1
]}

Hunt, Kelly K. ^{[1
]}

Ames, Frederick C. ^{[1
]}

Kuerer, Henry M. ^{[1
]}

Lucci, Anthony ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Surg, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Anesthesia, Houston, TX 77030 USA

来源：

AMERICAN JOURNAL OF SURGERY | 2009年 / 198卷 / 05期

关键词：

Breast surgery; Paravertebral blocks; Regional anesthesia; Postoperative pain; Pain control; Length of stay; POSTOPERATIVE NAUSEA; GENERAL-ANESTHESIA; INJECTION; ANALGESIA;

D O I：

10.1016/j.amjsurg.2008.11.043

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

BACKGROUND: The goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery. METHODS: Patients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain scores assessed. RESULTS: Eighty patients were randomized (41 to GA and 39 to PVB with GA). Operative times were not significantly different between groups. Pain scores were lower after PVB compared to GA at 1 hour (1 vs 3, P = .006) and 3 hours (0 vs 2, P = .001) but not at later time points. The overall worst pain experienced was lower with PVB (3 vs 5, P = .02). More patients were pain-free in the PVB group at 1 hour (44% vs 17%, P = .014) and 3 hours (54% vs 17%, P = .005) postoperatively. CONCLUSIONS: PVB significantly decreases postoperative pain up to 3 hours after breast cancer surgery. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：720 / 725

页数：6

共 16 条

[1]

BOUGHEY JC, BREAST J IN PRESS

[2]

COHEN MM, 1994, ANESTH ANALG, V78, P7

[3]

Sensory blockade after thoracic paravertebral injection of ropivacaine or bupivacaine [J].

Hura, G. ;

Knapik, P. ;

Misiolek, H. ;

Krakus, A. ;

Karpe, J. .

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2006, 23 (08) :658-664

[4]

Postoperative nausea and vomiting in women following breast surgery: an audit [J].

Jaffe, SM ;

Campbell, P ;

Bellman, M ;

Baildam, A .

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2000, 17 (04) :261-264

[5]

Cancer statistics, 2008 [J].

Jemal, Ahmedin ;

Siegel, Rebecca ;

Ward, Elizabeth ;

Hao, Yongping ;

Xu, Jiaquan ;

Murray, Taylor ;

Thun, Michael J. .

CA-A CANCER JOURNAL FOR CLINICIANS, 2008, 58 (02) :71-96

[6]

Single-injection paravertebral block before general anesthesia enhances analgesia after breast cancer surgery with and without associated lymph node biopsy [J].

Kairaluoma, PM ;

Bachmann, MS ;

Korpinen, AK ;

Rosenberg, PH ;

Pere, PJ .

ANESTHESIA AND ANALGESIA, 2004, 99 (06) :1837-1843

[7]

Karanikolas M, 2000, Anesthesiol Clin North Am, V18, P575, DOI 10.1016/S0889-8537(05)70181-4

[8]

Thoracic paravertebral block for breast surgery [J].

Klein, SM ;

Bergh, A ;

Steele, SM ;

Georgiade, GS ;

Greengrass, RA .

ANESTHESIA AND ANALGESIA, 2000, 90 (06) :1402-1405

[9]

PARAVERTEBRAL BLOCKADE - FAILURE RATE AND COMPLICATIONS [J].

LONNQVIST, PA ;

MACKENZIE, J ;

SONI, AK ;

CONACHER, ID .

ANAESTHESIA, 1995, 50 (09) :813-815

[10]

Thoracic paravertebral B-lock for breast cancer surgery: A randomized double-blind study [J].

Moller, Jytte F. ;

Nikolajsen, Lone ;

Rodt, Svein Aage ;

Ronning, Hanne ;

Carlsson, Palle S. .

ANESTHESIA AND ANALGESIA, 2007, 105 (06) :1848-1851

← 1 2 →