Expeditious formation of 1,2,4-triazine derivatives via a thioisomunchnone cycloaddition reaction

被引：15

作者：

Arévalo, MJ

Avalos, M

Babiano, R

Cintas, P

Hursthouse, MB

Jiménez, JL ^{[1
]}

Light, ME

López, I

Palacios, JC

机构：

[1] Univ Extremadura, Fac Ciencias, Dept Quim Organ, E-06071 Badajoz, Spain

[2] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(99)01837-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel type of heterocyclization reaction involving the [3+2] cycloaddition of N,N-dialkylamino-substituted thioisomunchnones with azodicarboxylates gives rise to 1,2,4-triazine derivatives after a selective fragmentation pathway of the transient cycloadducts. The X-ray analysis of 7 accounts for the fate of this particular transformation. An asymmetric version using chiral carbohydrate-based thioisomunchnones has also been disclosed. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：8675 / 8678

页数：4

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