Gastric MALT-lymphoma and Helicobacter pylori infection

被引：30

作者：

Bayerdorffer, E

Miehlke, S

Neubauer, A

Stolte, M

机构：

[1] HUMBOLDT UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW,DEPT HEMATOL & ONCOL,BERLIN,GERMANY

[2] KLINIKUM BAYREUTH,INST PATHOL,BAYREUTH,GERMANY

来源：

ALIMENTARY PHARMACOLOGY & THERAPEUTICS | 1997年 / 11卷

关键词：

D O I：

10.1046/j.1365-2036.11.s1.12.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The presence of lymphoid tissue in the gastric mucosa is virtually pathognomonic of Helicobacter pylori infection. This lymphoid tissue has mucosa-associated lymphoid tissue (MALT) characteristics suggesting that H. pylori infection may represent a stimulus for the growth of gastric MALT lymphoma. H. pylori can be detected in more than 90% of patients with low-grade gastric MALT lymphoma supporting the aetiological role of the organism, The strongest evidence for the significance of H. pylori in the pathogenesis of low aetological-grade gastric MALT lymphoma is provided by clinical studies showing that cure of H. pylori infection is followed by a complete regression of these tumours in most patients. This paper reviews the current knowledge about antibacterial treatment of low-grade gastric MALT lymphoma, and immunological and molecular aspects in the pathogenesis of the disease.

引用

页码：89 / 94

页数：6

共 37 条

[1] REGRESSION OF PRIMARY GASTRIC LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID-TISSUE TYPE AFTER CURE OF HELICOBACTER-PYLORI INFECTION
BAYERDORFFER, E
NEUBAUER, A
RUDOLPH, B
THIEDE, C
LEHN, N
EIDT, S
STOLTE, M
[J]. LANCET, 1995, 345 (8965): : 1591 - 1594
[2] BAYERDORFFER E, 1996, GASTROENTEROLOGY, V110, pA490
[3] GENETIC ABNORMALITIES DURING TRANSITION FROM HELICOBACTER-PYLORI-ASSOCIATED GASTRITIS TO LOW-GRADE MALTOMA
CALVERT, R
RANDERSON, J
EVANS, P
CAWKWELL, L
LEWIS, F
DIXON, MF
JACK, A
OWEN, R
SHIACH, C
MORGAN, GJ
[J]. LANCET, 1995, 345 (8941): : 26 - 27
[4] CARBONE PP, 1971, CANCER RES, V31, P1860
[5] DRAGOSICS B, 1985, CANCER, V55, P1060, DOI 10.1002/1097-0142(19850301)55:5<1060::AID-CNCR2820550523>3.0.CO
[6] 2-8
[7] ENNO A, 1995, AM J PATHOL, V147, P217
[8] HALL PA, 1988, LANCET, V2, P985
[9] HAYES J, 1989, CANCER, V63, P2073, DOI 10.1002/1097-0142(19890515)63:10<2073::AID-CNCR2820631033>3.0.CO
[10] 2-N

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