Metabolism and developmental competence of the preimplantation embryo

被引：69

作者：

Houghton, FD ^{[1
]}

Leese, HJ ^{[1
]}

机构：

[1] Univ York, Dept Biol, York YO10 5YW, N Yorkshire, England

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2004年 / 115卷

关键词：

preimplantation embryo metabolism; oxygen consumption; ATP; reactive oxygen species; amino acid turnover;

D O I：

10.1016/j.ejogrb.2004.01.019

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In vitro fertilisation (IVF) has permitted many thousands of couples to conceive world-wide yet is limited by low success rates and a confounding high multiple birth rate due to the transfer of more than one embryo. These problems could be overcome if single embryos of known developmental competence could be selected for replacement. It is clear that current embryo selection methods, which rely on morphological appearance alone, are poor predictors of viability. Metabolism is intrinsic to embryo health and much research has concentrated on developing a non-invasive metabolic marker of developmental competence. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S92 / S96

页数：5

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