Ten new antifouling briarane diterpenoids from the South China Sea gorgonian Junceella juncea

被引：103

作者：

Qi, Shu-Hua

Zhang, Si

Qian, Pei-Yuan

Xiao, Zhi-Hui

Li, Ming-Yi

机构：

[1] Chinese Acad Sci, S China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Biol, CML Clearwater Bay, Hong Kong, Hong Kong, Peoples R China

来源：

TETRAHEDRON | 2006年 / 62卷 / 39期

基金：

中国国家自然科学基金;

关键词：

Junceella juncea; briarane diterpenoids; antifouling; structure-activity relationship;

D O I：

10.1016/j.tet.2006.07.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Ten new antifouling briarane diterpenoids, juncins R-ZI (1-10) were isolated from the South China Sea gorgonian coral Junceella juncea. The structures of these new compounds were established by extensive spectroscopic analysis, including 1D and 2D NMR data. Compounds 1-10 all showed potent antifouling activities against the larval settlement of barnacle Balanus amphitrite at nontoxic concentrations with EC50 values of 0.004, 0.34, 2.65, 1.61, 3.77, 21.06, 0.004, 0.14, 1.47, and 0.51 mu g mL(-1). The structure-activity relationship was discussed. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：9123 / 9130

页数：8

共 20 条

[1]

Juncins I-M, five new briarane diterpenoids from the Indian Ocean -: Gorgonian Junceella juncea Pallas [J].