Synthesis of novel substituted isoquinolones

被引：33

作者：

Briet, N ^{[1
]}

Brookes, MH ^{[1
]}

Davenport, RJ ^{[1
]}

Galvin, FCA ^{[1
]}

Gilbert, PJ ^{[1
]}

Mack, SR ^{[1
]}

Sabin, V ^{[1
]}

机构：

[1] Celltech R&D, Cambridge CB1 6GS, England

来源：

TETRAHEDRON | 2002年 / 58卷 / 29期

关键词：

substituted isoquinolones; curtius rearrangement; isoquinoline N-oxide rearrangement;

D O I：

10.1016/S0040-4020(02)00573-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel substituted isoquinolones have been synthesised. This has been achieved by two routes, either Curtius rearrangment of cinnamic acids or via an isoquinoline N-oxide. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：5761 / 5766

页数：6

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