ARF proteins: roles in membrane traffic and beyond

被引：1139

作者：

D'Souza-Schorey, C ^{[1
]}

Chavrier, P

机构：

[1] Univ Notre Dame, Dept Biol Sci, Notre Dame, IN 46556 USA

[2] Univ Notre Dame, Walther Canc Inst, Notre Dame, IN 46556 USA

[3] Inst Curie, CNRS, Membrane & Cytoskeleton Dynam Grp, UMR 144, F-75231 Paris, France

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 05期

关键词：

D O I：

10.1038/nrm1910

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

The ADP-ribosylation factor (ARF) small GTPases regulate vesicular traffic and organelle structure by recruiting coat proteins, regulating phospholipid metabolism and modulating the structure of actin at membrane surfaces. Recent advances in our understanding of the signalling pathways that are regulated by ARF1 and ARF6, two of the best characterized ARF proteins, provide a molecular context for ARF protein function in fundamental biological processes, such as secretion, endocytosis, phagocytosis, cytokinesis, cell adhesion and tumour-cell invasion.

引用

页码：347 / 358

页数：12

共 208 条

[1]

ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosis [J].

Aikawa, Y ;

Martin, TFJ .

JOURNAL OF CELL BIOLOGY, 2003, 162 (04) :647-659

[2]

Separation of membrane trafficking and actin remodeling functions of ARF6 with an effector domain mutant [J].

Al-Awar, O ;

Radhakrishna, H ;

Powell, NN ;

Donaldson, JG .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (16) :5998-6007

[3]

ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth [J].

Albertinazzi, C ;

Za, L ;

Paris, S ;

de Curtis, I .

MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (04) :1295-1307

[4]

ADP-ribosylation factor 6 and endocytosis at the apical surface of Madin-Darby canine kidney cells [J].

Altschuler, Y ;

Liu, SH ;

Katz, L ;

Tang, K ;

Hardy, S ;

Brodsky, F ;

Apodaca, G ;

Mostov, K .

JOURNAL OF CELL BIOLOGY, 1999, 147 (01) :7-12

[5]

AMOR JC, 1994, NATURE, V372, P704, DOI 10.1038/372704a0

[6]

The KDEL receptor, ERD2, regulates intracellular traffic by recruiting a GTPase-activating protein for ARF1 [J].

Aoe, T ;

Cukierman, E ;

Lee, A ;

Cassel, D ;

Peters, PJ ;

Hsu, VW .

EMBO JOURNAL, 1997, 16 (24) :7305-7316

[7]

Recycling of raft-associated prohormone sorting receptor carboxypeptidase E requires interaction with ARF6 [J].

Arnaoutova, I ;

Jackson, CL ;

Al-Awar, MS ;

Donaldson, JG ;

Loh, YP .

MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (11) :4448-4457

[8]

A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1 [J].

Ashery, U ;

Koch, H ;

Scheuss, V ;

Brose, N ;

Rettig, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (03) :1094-1099

[9]

Site-specific cross-linking reveals a differential direct interaction of class 1, 2, and 3 ADP-ribosylation factors with adaptor protein complexes 1 and 3 [J].

Austin, C ;

Boehm, M ;

Tooze, SA .

BIOCHEMISTRY, 2002, 41 (14) :4669-4677

[10]

ARF6 GTPase controls bacterial invasion by actin remodelling [J].

Balañá, ME ;

Niedergang, F ;

Subtil, A ;

Alcover, A ;

Chavrier, P ;

Dautry-Varsat, A .

JOURNAL OF CELL SCIENCE, 2005, 118 (10) :2201-2210

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