Serologic evidence of H1 swine influenza virus infection in swine farm residents and employees

被引：113

作者：

Olsen, CW

Brammer, L

Easterday, BC

Arden, N

Belay, E

Baker, I

Cox, NJ

机构：

[1] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI 53706 USA

[2] Ctr Dis Control & Prevent, Atlanta, GA USA

[3] Texas A&M Univ, Coll Med, College Stn, TX 77843 USA

来源：

EMERGING INFECTIOUS DISEASES | 2002年 / 8卷 / 08期

关键词：

D O I：

10.3201/eid0808.010474

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemagglutination-inhibition (HI) antibody titers greater than or equal to40 to swine influenza viruses (17/74) was significantly higher (p<0.001) than the number of seropositive urban control samples (1/114). The geometric mean serum HI antibody titers to swine influenza viruses were also significantly higher (p<0.001) among the farm participants. Swine virus seropositivity was significantly (p<0.05) associated with being a farm owner or a farm family member, living on a farm, or entering the swine barn greater than or equal to4 days/week. Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses.

引用

页码：814 / 819

页数：6

共 37 条

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