Behavioral symptoms in mild cognitive impairment

被引:200
作者
Feldman, H
Scheltens, P
Scarpini, E
Hermann, N
Mesenbrink, P
Mancione, L
Tekin, S
Lane, R
Ferris, S
机构
[1] Univ British Columbia, Vancouver Hosp & Hlth Sci Ctr, Div Neurol, Vancouver, BC, Canada
[2] Vrije Univ Amsterdam, Med Ctr, Dept Neurol, Alzheimer Ctr, Amsterdam, Netherlands
[3] Univ Milan, IRCCS Maggiore Hosp, Dept Neurol, I-20122 Milan, Italy
[4] Univ Toronto, Div Geriatr Psychiat, Toronto, ON, Canada
[5] Novartis Pharmaceut Corp, E Hanover, NJ USA
[6] NYU, Med Ctr, Ctr Aging, New York, NY USA
关键词
D O I
10.1212/01.WNL.0000118301.92105.EE
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors investigated neuropsychiatric symptoms in mild cognitive impairment (MCI) from baseline data of the Investigation in the Delay to Diagnosis of AD with Exelon (InDDEx) study (n=1,010). Neuropsychiatric symptoms were reported in 59% of subjects (Neuropsychiatric Inventory [NPI]). NPI+ subjects had significantly greater impairment on global, cognitive, and functional scores than NPI- subjects. The presence of neuropsychiatric symptoms appears to be a marker of MCI severity.
引用
收藏
页码:1199 / 1201
页数:3
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