Cefepime MIC as a predictor of the extended-spectrum β-lactamase type in Klebsiella pneumoniae, Taiwan

被引：38

作者：

Yu, WL

Pfaller, MA

Winokur, PL

Jones, RN

机构：

[1] China Med Coll Hosp, Taichung, Taiwan

[2] Univ Iowa, Coll Med, Iowa City, IA USA

[3] JONES Grp, JMI Labs, N Liberty, IA 52317 USA

[4] Tufts Univ, Sch Med, Boston, MA 02111 USA

来源：

EMERGING INFECTIOUS DISEASES | 2002年 / 8卷 / 05期

关键词：

D O I：

10.3201/eid0805.010346

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To guide selection of carbapenems or fourth-generation cephalosporins as therapy, 110 Klebsiella pneumoniae isolates with extended-spectrum beta-lactamases from Taiwan were characterized by phenotypic (MICs), molecular, and chemical methods. MIC patterns of ceftazidime and cefepime clearly differentiate strains treatable by cefepime and those capable of efficiently hydrolyzing available cephalosporins (CTX-M series and SHV-types). Continued use of cefepime appears to be a treatment option in cases for which MIC results are available and interpreted by the criteria presented.

引用

收藏

页码：522 / 524

页数：3

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