共 154 条
Gait dynamics in Parkinson's disease: Common and distinct behavior among stride length, gait variability, and fractal-like scaling
被引:449
作者:
Hausdorff, Jeffrey M.
[1
,2
,3
]
机构:
[1] Tel Aviv Sourasky Med Ctr, Movement Disorders Unit, Lab Gait & Neurodynam, Dept Neurol, IL-64239 Tel Aviv, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Dept Phys Therapy, IL-69978 Tel Aviv, Israel
[3] Harvard Univ, Sch Med, Boston, MA 02115 USA
来源:
关键词:
LONG-RANGE CORRELATIONS;
RHYTHMIC AUDITORY-STIMULATION;
HEART-RATE-VARIABILITY;
BILATERAL COORDINATION;
HUMAN WALKING;
OLDER-ADULTS;
COGNITIVE IMPAIRMENT;
DOPAMINE TRANSPORTER;
PHYSICAL-THERAPY;
ENTROPY ANALYSIS;
D O I:
10.1063/1.3147408
中图分类号:
O29 [应用数学];
学科分类号:
070104 [应用数学];
摘要:
Parkinson's disease (PD) is a common, debilitating neurodegenerative disease. Gait disturbances are a frequent cause of disability and impairment for patients with PD. This article provides a brief introduction to PD and describes the gait changes typically seen in patients with this disease. A major focus of this report is an update on the study of the fractal properties of gait in PD, the relationship between this feature of gait and stride length and gait variability, and the effects of different experimental conditions on these three gait properties. Implications of these findings are also briefly described. This update highlights the idea that while stride length, gait variability, and fractal scaling of gait are all impaired in PD, distinct mechanisms likely contribute to and are responsible for the regulation of these disparate gait properties. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3147408]
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