Hydrogen-bond-promoted hetero-Diels-Alder reactions of unactivated ketones

被引：156

作者：

Huang, Y ^{[1
]}

Rawal, VH ^{[1
]}

机构：

[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 33期

关键词：

D O I：

10.1021/ja0267627

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the first examples of hydrogen-bond-promoted acceleration of hetero-Diels-Alder reactions and the use of such catalysis for the hetero-Diels-Alder reactions of simple, unactivated ketones. Several spiro-fused dihydropyans were synthesized in good yields using this procedure. This activation protocol represents an attractive and operationally simple alternative to conventional, Lewis acid catalysis. Copyright © 2002 American Chemical Society.

引用

页码：9662 / 9663

页数：2

共 30 条

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[2]

BOGER DL, 1987, HETERO DIELSALDER ME, V47

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