Chromium picolinate products have been examined for different forms of chromium, using chromatographic separation and inductively coupled plasma mass spectrometric detection. The brands we evaluated contained no detectable amount of elemental chromium (VI), the toxic form. Since chromium picolinate might have other chromium forms as impurities, different products may contain different forms of chromium species. Compared with ion-exchange, reversed-phase chromatography showed excellent chromium recovery based on the amount stated on the product label.