The effect of dairy foods on CHD: a systematic review of prospective cohort studies

被引:57
作者
Gibson, Robert A. [1 ,2 ,3 ]
Makrides, Maria [1 ,2 ,4 ]
Smithers, Lisa G. [1 ,2 ,4 ,5 ]
Voevodin, Melanie [6 ]
Sinclair, Andrew J. [7 ]
机构
[1] Womens & Childrens Hlth Res Inst, Child Youth & Womens Hlth Serv, Adelaide, SA 5006, Australia
[2] Flinders Med Ctr, Bedford Pk, SA 5042, Australia
[3] Univ Adelaide, Sch Agr Food & Wine, Adelaide, SA 5064, Australia
[4] Univ Adelaide, Sch Paediat & Reprod Hlth, Adelaide, SA 5064, Australia
[5] Flinders Univ S Australia, Sch Paediat & Child Hlth, Bedford Pk, SA 5042, Australia
[6] Food Sch, Melbourne, Vic 3124, Australia
[7] Deakin Univ, Sch Exercise & Nutr Sci, Burwood, Vic 3125, Australia
基金
英国医学研究理事会;
关键词
Dairy foods; CHD; Myocardial infarction; Systematic reviews; CORONARY-HEART-DISEASE; DIETARY-FAT INTAKE; CARDIOVASCULAR-DISEASE; BLOOD-PRESSURE; PLASMA-CHOLESTEROL; MILK CONSUMPTION; CALCIUM INTAKE; SERUM-LIPIDS; FOLLOW-UP; RISK;
D O I
10.1017/S0007114509371664
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 [营养与食品卫生学];
摘要
There is interest in the degree to which fats in dairy foods contribute to CHD. We undertook a systematic review to investigate the effect of dairy consumption on CHD using prospective cohort studies. A systematic search of electronic databases identified studies relating dairy food intake in adulthood to episodes or death from CHD, IHD and myocardial infarction. Included studies were assessed for quality based on study methodology, validity of dietary assessment, success of follow-up, standardised assessment of CHD, IHD or myocardial infarction end points and appropriateness of statistical adjustment. Data from twelve cohorts involving >280000 subjects were included. Most studies had follow-up of >80%, adjusted statistically for three or more confounders and used standard criteria to determine end points. About half the studies used a validated FFQ, administered the FFQ more than once or had follow-up of >20 years. Fewer than half the studies involved subjects representative of the general population. Four of the twelve cohorts found no association between dairy intake and CHD. Eight studies reported varying relationships between different dairy foods and CHD or differential associations based on race, sex or over time. Although dairy foods contribute to the SFA composition of the diet, this systematic review could find no consistent evidence that dairy food consumption is associated with a higher risk of CHD. This could be due to the limited sensitivity of the dietary assessment methods to detect an effect of a single food in a mixed diet on complex clinical outcomes.
引用
收藏
页码:1267 / 1275
页数:9
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