Future risk of diabetes in mother and child after gestational diabetes mellitus

被引:162
作者
Damm, Peter [1 ]
机构
[1] Univ Copenhagen, Rigshosp, Dept Obstet & Endocrinol, Ctr Pregnant Women Diabet, DK-2100 Copenhagen, Denmark
关键词
Gestational diabetes mellitus; Intrauterine hyperglycemia; Long-term risk; LIFE-STYLE; WOMEN; PREVALENCE; POPULATION; PREVENTION; PREGNANCY; OBESITY;
D O I
10.1016/j.ijgo.2008.11.025
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Gestational diabetes mellitus (GDM) is a common pregnancy complication with increased maternal and perinatal morbidity. However, significant long-term morbidity also exists for the mother and offspring. Women with previous GDM have a very high risk of developing overt diabetes, primarily type 2 diabetes, later in life. Moreover, the risk of the metabolic syndrome is increased 3 fold in these women. Their offspring have in 8-fold risk of diabetes/prediabetes at 19-27 years of age. Thus, GDM is part of a Vicious circle which increases the development of diabetes in the coming generations. (C) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:S25 / S26
页数:2
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