Fluoro alcohol as reaction medium:: one-pot synthesis of β-hydroxy sulfoxides from epoxides

被引：83

作者：

Kesavan, V ^{[1
]}

Bonnet-Delpon, D ^{[1
]}

Bégué, JP ^{[1
]}

机构：

[1] Ctr Etud Pharmaceut, CNRS, Lab BIOCIS, F-92296 Chatenay Malabry, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(00)00305-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

beta-Hydroxy sulfoxides were obtained in one-pot synthesis by the ring opening of oxiranes with thiols in hexafluoroisopropanol (HFIP) without any catalyst, followed by in situ oxidation under neutral conditions. The reaction is anti-selective. beta-Hydroxy sulfoxides were transformed by pyrolysis in the corresponding allylic alcohols. (C) 2000 Elsevier Science Ltd. Ail rights reserved.

引用

页码：2895 / 2898

页数：4

共 25 条

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