BioPortal: ontologies and integrated data resources at the click of a mouse

被引：447

作者：

Noy, Natalya F. ^{[1
]}

Shah, Nigam H. ^{[1
]}

Whetzel, Patricia L. ^{[1
]}

Dai, Benjamin ^{[1
]}

Dorf, Michael ^{[1
]}

Griffith, Nicholas ^{[1
]}

Jonquet, Clement ^{[1
]}

Rubin, Daniel L. ^{[1
]}

Storey, Margaret-Anne ^{[2
]}

Chute, Christopher G. ^{[3
]}

Musen, Mark A. ^{[1
]}

机构：

[1] Stanford Univ, Stanford Ctr Biomed Informat Res, Stanford, CA 94305 USA

[2] Univ Victoria, Dept Comp Sci, Victoria, BC, Canada

[3] Mayo Clin, Dept Biomed Informat, Rochester, MN USA

来源：

NUCLEIC ACIDS RESEARCH | 2009年 / 37卷

基金：

美国国家卫生研究院;

关键词：

CONTROLLED VOCABULARY QUERIES; LOOKUP SERVICE;

D O I：

10.1093/nar/gkp440

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biomedical ontologies provide essential domain knowledge to drive data integration, information retrieval, data annotation, natural-language processing and decision support. BioPortal (http://bioportal.bioontology.org) is an open repository of biomedical ontologies that provides access via Web services and Web browsers to ontologies developed in OWL, RDF, OBO format and Protege frames. BioPortal functionality includes the ability to browse, search and visualize ontologies. The Web interface also facilitates community-based participation in the evaluation and evolution of ontology content by providing features to add notes to ontology terms, mappings between terms and ontology reviews based on criteria such as usability, domain coverage, quality of content, and documentation and support. BioPortal also enables integrated search of biomedical data resources such as the Gene Expression Omnibus (GEO), ClinicalTrials.gov, and ArrayExpress, through the annotation and indexing of these resources with ontologies in BioPortal. Thus, BioPortal not only provides investigators, clinicians, and developers 'one-stop shopping' to programmatically access biomedical ontologies, but also provides support to integrate data from a variety of biomedical resources.

引用

页码：W170 / W173

页数：4

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