Intraarterial therapies for primary liver cancer: state of the art

被引：11

作者：

Chapiro, Julius ^{[1
]}

Tacher, Vania ^{[1
]}

Geschwind, Jean-Francois ^{[1
]}

机构：

[1] Johns Hopkins Univ, Russell H Morgan Dept Radiol & Radiol Sci, Sect Vasc & Intervent Radiol, Sch Med,Johns Hopkins Hosp, Baltimore, MD 21287 USA

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2013年 / 13卷 / 10期

关键词：

carcinoma; cholangiocarcinoma; DEB-TACE; hepatocellular; intraarterial therapy; liver cancer; radioembolization; sorafenib; TACE; DRUG-ELUTING BEADS; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; UNRESECTABLE HEPATOCELLULAR-CARCINOMA; PHASE-II TRIAL; TRANSARTERIAL CHEMOEMBOLIZATION; Y-90; MICROSPHERES; INTRAHEPATIC CHOLANGIOCARCINOMA; TUMOR RESPONSE; INITIAL-EXPERIENCE; ANIMAL-MODEL;

D O I：

10.1586/14737140.2013.845528

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Image-guided intraarterial therapies play an important role in the treatment of patients with hepatic malignancies. These therapies provide the dual benefit of reduced systemic toxicity and effective local tumor control. As a result, procedures such as transarterial chemoembolization have been included in the official treatment guidelines for hepatocellular carcinoma (HCC) and are fully accepted for the treatment of patients with intermediate stage disease. In this review, we will describe the scientific rationale for intraarterial therapies and discuss the available clinical evidence for primary liver cancer. Finally, we will touch on the current trends consisting of combining intraarterial approaches with systemically administered targeted agents.

引用

页码：1157 / 1167

页数：11

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