Platinum complexes of terpyridine: Interaction and reactivity with biomolecules

被引：125

作者：

Cummings, Scott D. ^{[1
]}

机构：

[1] Kenyon Coll, Dept Chem, Gambier, OH 43022 USA

来源：

COORDINATION CHEMISTRY REVIEWS | 2009年 / 253卷 / 9-10期

关键词：

Platinum complexes; Terdentate nitrogen ligands; Intercalation; DNA; Protein labeling; CRUZI TRYPANOTHIONE REDUCTASE; DNA-INTERCALATING AGENT; CRYSTAL-STRUCTURE; 2,2'/6',2''-TERPYRIDINEPLATINUM(II) COMPLEXES; METALLOINTERCALATION REAGENT; TRYPANOSOMA-CRUZI; TRANSITION-METAL; NUCLEIC-ACIDS; CYTOCHROMES-C; (2,2'/6',2''-TERPYRIDINE)PLATINUM(II) COMPLEXES;

D O I：

10.1016/j.ccr.2008.12.009

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学];

摘要：

Research on the coordination chemistry of Pt(II) terpyridine complexes spans more than 75 years, with significant recent work exploring the bioinorganic and medicinal chemistry of this diverse and versatile family of coordination Compounds. This paper reviews the research literature describing investigations of the interactions of Pt(II) terpyridine complexes with nucleic acids and proteins. (C) 2008 Elsevier B.V. All rights reserved.

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页码：1495 / 1516

页数：22

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