Effect of human hydrosalpinx fluid on murine embryo development and implantation

被引：46

作者：

Rawe, VJ ^{[1
]}

Liu, JE ^{[1
]}

Shaffer, S ^{[1
]}

Compton, MG ^{[1
]}

Garcia, JE ^{[1
]}

Katz, E ^{[1
]}

机构：

[1] GREATER BALTIMORE MED CTR,DEPT GYNECOL,GREATER BALTIMORE FACIL CTR,BALTIMORE,MD 21204

来源：

FERTILITY AND STERILITY | 1997年 / 68卷 / 04期

关键词：

hydrosalpinx; IVF; implantation; embryo;

D O I：

10.1016/S0015-0282(97)00319-1

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To determine the effect of hydrosalpinx fluid-containing medium on murine embryo development and implantation. Design: The development of one-, two-, and four-cell mouse embryos in medium containing 5%, 10%, and 20% of human hydrosalpinx fluid was observed. Implantation rates of mouse embryos transferred into the uterine horn with hydrosalpinx fluid-containing media were determined. Setting: Private hospital-based fertility center and IVF program. Main Outcome Measure(s): Percentage of embryos continuing cell division and implantation rates after ET. Result(s): Hydrosalpinx fluid in culture medium affected embryo development in a dose-dependent fashion. The injection of hydrosalpinx fluid-containing medium into the uterine horn did not affect embryo implantation. Conclusion(s): Hydrosalpinx fluid negatively affects murine embryo development, but its presence in the uterine horn at ET did not affect implantation. (C) 1997 by American Society for Reproductive Medicine.

引用

页码：668 / 670

页数：3

共 4 条

[1] Deleterious effect of the presence of hydrosalpinx on implantation and pregnancy rates with in vitro fertilization [J].

Katz, E ;

Akman, MA ;

Damewood, MD ;

Garcia, JE .

FERTILITY AND STERILITY, 1996, 66 (01) :122-125

[2]

LESSEY BA, 1994, P AM FERT SOC SAN AN

[3] THE IN-VITRO AND IN-VIVO DEVELOPMENTAL POTENTIAL OF FROZEN AND NON-FROZEN BIOPSIED 8-CELL MOUSE EMBRYOS [J].

LIU, J ;

VANDENABBEEL, E ;

VANSTEIRTEGHEM, A .

HUMAN REPRODUCTION, 1993, 8 (09) :1481-1486

[4]

MUKHERJEE T, FERTIL STERIL, V66, P851

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