Near-infrared Raman spectrometer systems for human tissue studies

被引：103

作者：

Brennan, JF ^{[1
]}

Wang, Y ^{[1
]}

Dasari, RR ^{[1
]}

Feld, MS ^{[1
]}

机构：

[1] MIT,GEORGE R HARRISON SPECT LAB,LASER BIOMED RES CTR,CAMBRIDGE,MA 02139

来源：

APPLIED SPECTROSCOPY | 1997年 / 51卷 / 02期

关键词：

Raman spectroscopy; optical-fiber sampling; biomedical spectroscopy; CCD detectors; instrumentation; calibration techniques;

D O I：

10.1366/0003702971940134

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

We have built two types of instruments for near-infrared Raman spectroscopy studies of human tissues, one for laboratory measurements and one for clinical use. The laboratory systems are designed to collect the highest quality spectra possible and allow different excitation/collection wavelengths to be studied. The clinical systems are designed to collect spectra via optical fibers within a few seconds and to be mobile and hospital-compatible. These systems are capable of detecting weak near-infrared Raman bands hidden in large background signals. Calibration and background subtraction procedures are described, and system performance is evaluated.

引用

页码：201 / 208

页数：8

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