Oxidative N-demethylation of N,N-dimethylanilines catalysed by lignin peroxidase:: a mechanistic insight by a kinetic deuterium isotope effect study

被引：25

作者：

Baciocchi, E

Gerini, MF

Lanzalunga, O

Lapi, A

Mancinelli, S

Mencarelli, P

机构：

[1] Univ Roma La Sapienza, Dipartimento Chim, I-00185 Rome, Italy

[2] Univ Roma La Sapienza, Dipartimento Chim, I-00185 Rome, Italy

[3] Univ Roma La Sapienza, Ctr CNR Studio Meccanismi Reaz, I-00185 Rome, Italy

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 05期

关键词：

D O I：

10.1039/a908394d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Lignin peroxidase can catalyse the N-demethylation of N,N-dimethylanilines by an electron transfer mechanism, where the deprotonation of the intermediate radical cation is also an enzymatic process.

引用

页码：393 / 394

页数：2

共 22 条

[1] LIGNIN PEROXIDASE-CATALYZED OXIDATION OF SULFONATED AZO DYES GENERATES NOVEL SULFOPHENYL HYDROPEROXIDES [J].

CHIVUKULA, M ;

SPADARO, JT ;

RENGANATHAN, V .

BIOCHEMISTRY, 1995, 34 (23) :7765-7772

[2]

EVERSE J, 1991, PEROXIDASES CHEM BIO, V1

[3]

Everse J., 1991, PEROXIDASES CHEM BIO, V2

[4]

Frisch M.J., 1995, GAUSSIAN 94

[5] AN EXTRACELLULAR H2O2-REQUIRING ENZYME PREPARATION INVOLVED IN LIGNIN BIODEGRADATION BY THE WHITE ROT BASIDIOMYCETE PHANEROCHAETE-CHRYSOSPORIUM [J].

GLENN, JK ;

MORGAN, MA ;

MAYFIELD, MB ;

KUWAHARA, M ;

GOLD, MH .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 114 (03) :1077-1083

[6] EVIDENCE FOR VERATRYL ALCOHOL AS A REDOX MEDIATOR IN LIGNIN PEROXIDASE-CATALYZED OXIDATION [J].

GOODWIN, DC ;

AUST, SD ;

GROVER, TA .

BIOCHEMISTRY, 1995, 34 (15) :5060-5065

[7]

HAEMMERLI SD, 1986, J BIOL CHEM, V261, P6900

[8] H2O2 RECYCLING DURING OXIDATION OF THE ARYLGLYCEROL BETA-ARYL ETHER LIGNIN STRUCTURE BY LIGNIN PEROXIDASE AND GLYOXAL OXIDASE [J].

HAMMEL, KE ;

MOZUCH, MD ;

JENSEN, KA ;

KERSTEN, PJ .

BIOCHEMISTRY, 1994, 33 (45) :13349-13354

[9] Redox and acidity properties of alkyl- and arylamine radical cations and the corresponding aminyl radicals [J].

Jonsson, M ;

Wayner, DDM ;

Lusztyk, J .

JOURNAL OF PHYSICAL CHEMISTRY, 1996, 100 (44) :17539-17543

[10] OXIDATION OF DIBENZO-P-DIOXIN BY LIGNIN PEROXIDASE FROM THE BASIDIOMYCETE PHANEROCHAETE-CHRYSOSPORIUM [J].

JOSHI, DK ;

GOLD, MH .

BIOCHEMISTRY, 1994, 33 (36) :10969-10976

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