Synthesis of 1H-2-naphtho[2,3-c]thiapyran-5,10-dione-2,2-dioxide, a 2-sulfone analogue of pentalongin

被引:10
作者
Kesteleyn, B [1 ]
De Kimpe, N [1 ]
机构
[1] State Univ Ghent, Dept Organ Chem, Fac Agr & Appl Biol Sci, B-9000 Ghent, Belgium
关键词
D O I
10.1016/S0040-4039(99)02146-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of 1H-2-naphtho[2,3-c] thiapyran-5,10-dione-2,2-dioxide (2), a 2-sulfone derivative of the natural pyranonaphthoquinone pentalongin (1), was accomplished using the acid-catalysed cyclisation of the naphthoquinone sulfone acetal 6 as a key step in the synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:755 / 758
页数:4
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