A novel RNA-binding motif in influenza A virus non-structural protein 1

被引：94

作者：

Chien, CY

Tejero, R

Huang, YP

Zimmerman, DE

Rios, CB

Krug, RM

Montelione, GT

机构：

[1] RUTGERS STATE UNIV,CTR ADV BIOTECHNOL & MED,PISCATAWAY,NJ 08854

[2] RUTGERS STATE UNIV,DEPT MOL BIOL & BIOCHEM,PISCATAWAY,NJ 08854

[3] UNIV VALENCIA,DEPT QUIM FIS,E-46100 BURJASSOT,VALENCIA,SPAIN

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 11期

关键词：

D O I：

10.1038/nsb1197-891

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold, Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.

引用

页码：891 / 895

页数：5

共 24 条

[1] STRUCTURE OF THE CO1E1 ROP PROTEIN AT 1.7 A RESOLUTION
BANNER, DW
KOKKINIDIS, M
TSERNOGLOU, D
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1987, 196 (03) : 657 - 675
[2] alpha helix-RNA major groove recognition in an HIV-1 Rev peptide RRE RNA complex
Battiste, JL
Mao, HY
Rao, NS
Tan, RY
Muhandiram, DR
Kay, LE
Frankel, AD
Williamson, JR
[J]. SCIENCE, 1996, 273 (5281) : 1547 - 1551
[3] THE 2.9 ANGSTROM CRYSTAL-STRUCTURE OF THERMUS-THERMOPHILUS SERYL-TRANSFER-RNA SYNTHETASE COMPLEXED WITH TRNA(SER)
BIOU, V
YAREMCHUK, A
TUKALO, M
CUSACK, S
[J]. SCIENCE, 1994, 263 (5152) : 1404 - 1410
[4] INFLUENZA B-VIRUS GENOME - SEQUENCES AND STRUCTURAL ORGANIZATION OF RNA SEGMENT-8 AND THE MESSENGER-RNAS CODING FOR THE NS1 AND NS2 PROTEINS
BRIEDIS, DJ
LAMB, RA
[J]. JOURNAL OF VIROLOGY, 1982, 42 (01) : 186 - 193
[5] RNA recognition and translational regulation by a homeodomain protein
Dubnau, J
Struhl, G
[J]. NATURE, 1996, 379 (6567) : 694 - 699
[6] EFFICIENT COMPUTATION OF 3-DIMENSIONAL PROTEIN STRUCTURES IN SOLUTION FROM NUCLEAR-MAGNETIC-RESONANCE DATA USING THE PROGRAM DIANA AND THE SUPPORTING PROGRAMS CALIBA, HABAS AND GLOMSA
GUNTERT, P
BRAUN, W
WUTHRICH, K
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1991, 217 (03) : 517 - 530
[7] PROTEIN-STRUCTURE COMPARISON BY ALIGNMENT OF DISTANCE MATRICES
HOLM, L
SANDER, C
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1993, 233 (01) : 123 - 138
[8] THE SOLUTION STRUCTURE OF EGLIN-C BASED ON MEASUREMENTS OF MANY NOES AND COUPLING-CONSTANTS AND ITS COMPARISON WITH X-RAY STRUCTURES
HYBERTS, SG
GOLDBERG, MS
HAVEL, TF
WAGNER, G
[J]. PROTEIN SCIENCE, 1992, 1 (06) : 736 - 751
[9] CRYSTAL-STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8-A RESOLUTION - A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS
KISSINGER, CR
LIU, BS
MARTINBLANCO, E
KORNBERG, TB
PABO, CO
[J]. CELL, 1990, 63 (03) : 579 - 590
[10] LAMB RA, 1996, VIROLOGY, P1353

← 1 2 3 →