CD52 expression in mantle cell lymphoma

被引：9

作者：

Bass, AJ ^{[1
]}

Gong, J ^{[1
]}

Nelson, R ^{[1
]}

Rizzieri, DA ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Sch Med, Durham, NC 27710 USA

来源：

LEUKEMIA & LYMPHOMA | 2002年 / 43卷 / 02期

关键词：

mantle cell lymphoma; CD52; CAMPATH-1H; immunohistochemistry;

D O I：

10.1080/10428190290006125

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Mantle cell lymphoma is one of the most difficult to treat of all the non-Hodgkin's lymphomas. CAMPATH-1H, a humanized monoclonal antibody against the CD52 antigen, has been used with some success in other lymphoproliferative diseases, especially chronic lymphocytic leukemia. This report demonstrates that tumor samples from patients with mantle cell lymphoma express the CD52 antigen and suggests that CAMPATH-1H should be studied in patients with mantle cell lymphoma.

引用

页码：339 / 342

页数：4

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