Increased IL-23 receptor, TNF-α and IL-6 expression in individuals with the IL23R-IL12R132 locus polymorphism

被引：15

作者：

Cavus, Filiz ^{[1
]}

Ulusoy, Canan ^{[2
]}

Orcen, Arda ^{[2
]}

Gul, Ahmet ^{[3
]}

Tuzun, Erdem ^{[2
]}

Vural, Burcak ^{[1
]}

机构：

[1] Istanbul Univ, Expt Med Res Inst, Dept Genet, Istanbul, Turkey

[2] Istanbul Univ, Expt Med Res Inst, Dept Neurosci, Istanbul, Turkey

[3] Istanbul Univ, Istanbul Fac Med, Dept Internal Med, Div Rheumatol, Istanbul, Turkey

来源：

IMMUNOLOGY LETTERS | 2014年 / 160卷 / 01期

关键词：

Behcet's disease; IL-23; receptor; Autoinflammation; Cytokine; TNF-alpha; Polymorphism; BEHCETS-DISEASE; ASSOCIATION; IL10;

D O I：

10.1016/j.imlet.2014.01.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

引用

页码：96 / 98

页数：3

共 7 条

[1]

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases [J].

Akdis, Muebeccel ;

Burgler, Simone ;

Crameri, Reto ;

Eiwegger, Thomas ;

Fujita, Hiroyuki ;

Gomez, Enrique ;

Klunker, Sven ;

Meyer, Norbert ;

O'Mahony, Liam ;

Palomares, Oscar ;

Rhyner, Claudio ;

Quaked, Nadia ;

Schaffartzik, Anna ;

Van De Veen, Willem ;

Zeller, Sabine ;

Zimmermann, Maya ;

Akdis, Cezmi A. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2011, 127 (03) :701-U317

[2]

The IL23R A/GIn381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients [J].

Di Meglio, Paola ;

Villanova, Federica ;

Napolitano, Luca ;

Tosi, Isabella ;

Barberio, Manuela Terranova ;

Mak, Rose K. ;

Nutland, Sarah ;

Smith, Catherine H. ;

Barker, Jonathan N. W. N. ;

Todd, John A. ;

Nestle, Frank O. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2013, 133 (10) :2381-2389

[3]

Gul Ahmet, 2005, Current Drug Targets - Inflammation and Allergy, V4, P81, DOI 10.2174/1568010053622894

[4]

Na SY, 2013, CLIN EXP RHEUMATOL, V31, pS32

[5]

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease [J].

Remmers, Elaine F. ;

Cosan, Fulya ;

Kirino, Yohei ;

Ombrello, Michael J. ;

Abaci, Neslihan ;

Satorius, Colleen ;

Le, Julie M. ;

Yang, Barbara ;

Korman, Benjamin D. ;

Cakiris, Aris ;

Aglar, Oznur ;

Emrence, Zeliha ;

Azakli, Hulya ;

Ustek, Duran ;

Tugal-Tutkun, Ilknur ;

Akman-Demir, Gulsen ;

Chen, Wei ;

Amos, Christopher I. ;

Dizon, Michael B. ;

Kose, Afet Akdag ;

Azizlerli, Gulsevim ;

Erer, Burak ;

Brand, Oliver J. ;

Kaklamani, Virginia G. ;

Kaklamanis, Phaedon ;

Ben-Chetrit, Eldad ;

Stanford, Miles ;

Fortune, Farida ;

Ghabra, Marwen ;

Ollier, William E. R. ;

Cho, Young-Hun ;

Bang, Dongsik ;

O'Shea, John ;

Wallace, Graham R. ;

Gadina, Massimo ;

Kastner, Daniel L. ;

Gul, Ahmet .

NATURE GENETICS, 2010, 42 (08) :698-U78

[6]

Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behcet's disease [J].

Sugita, Sunao ;

Kawazoe, Yuko ;

Imai, Ayano ;

Yamada, Yukiko ;

Horie, Shintaro ;

Mochizuki, Manabu .

ARTHRITIS RESEARCH & THERAPY, 2012, 14 (03)

[7]

Association study of IL10 and IL23r-IL12RB2 in Iranian patients with Behcet's disease [J].

Xavier, Joana M. ;

Shahram, Farhad ;

Davatchi, Fereydoun ;

Rosa, Alexandra ;

Crespo, Jorge ;

Abdollahi, Bahar Sadeghi ;

Nadji, Abdolhadi ;

Jesus, Gorete ;

Barcelos, Filipe ;

Patto, Jose Vaz ;

Shafiee, Niloofar Mojarad ;

Ghaderibarim, Fahmida ;

Oliveira, Sofia A. .

ARTHRITIS AND RHEUMATISM, 2012, 64 (08) :2761-2772

← 1 →