Selectins: lectins that initiate cell adhesion under flow

被引：309

作者：

McEver, RP ^{[1
]}

机构：

[1] Oklahoma Med Res Fdn, Cardiovasc Biol Res Program, Oklahoma City, OK 73104 USA

[2] Univ Oklahoma, Hlth Sci Ctr, Dept Biochem & Mol Biol, Oklahoma Ctr Med Glycobiol, Oklahoma City, OK 73104 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(02)00367-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Interactions of selectins with cell-surface glycoconjugates mediate tethering and rolling adhesion of leukocytes and platelets on vascular surfaces. Recent studies have helped elucidate the molecular details of selectin-ligand interactions, the biosynthetic pathways for constructing selectin ligands, and the biophysical and cell biological features that modulate selectin-dependent rolling under flow.

引用

页码：581 / 586

页数：6

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