Beyond blood sugar: the potential of NMR-based metabonomics for type 2 human diabetes, and the horse as a possible model

被引：72

作者：

Hodavance, Michael S.

Ralston, Sarah L.

Pelczer, Istvan ^{[1
]}

机构：

[1] Princeton Univ, Dept Chem, Princeton, NJ 08544 USA

[2] Rutgers State Univ, Sch Biol & Environm Sci, Dept Anim Sci, New Brunswick, NJ 08981 USA

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2007年 / 387卷 / 02期

关键词：

metabonomics; type; 2; diabetes; horses; glucose tolerance; insulin resistance; NMR;

D O I：

10.1007/s00216-006-0979-z

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Metabonomic analysis is a powerful tool for identifying and characterizing metabolic disorders, for example type 2 diabetes and the metabolic syndrome. Nuclear magnetic resonance (NMR) spectroscopy is an essential tool for such analysis, with special benefits. The review assesses the current status and potential of NMR-based metabonomics of type 2 diabetes. The horse is proposed as a possible model for studying this condition and disease. Some examples are shown of horse blood analyses by NMR.

引用

页码：533 / 537

页数：5

共 16 条

[1]

H-1 NMR spectroscopy of human blood plasma [J].