Dynamic analysis of multivariate failure time data

被引:48
作者
Aalen, OO
Fosen, J
Weedon-Fekjær, H
Borgan, O
Husebye, E
机构
[1] Univ Oslo, Sect Med Stat, N-0317 Oslo, Norway
[2] Canc Registry Norway, N-0310 Oslo, Norway
[3] Univ Oslo, Dept Math, N-0316 Oslo, Norway
[4] Ullevaal Univ Hosp, Dept Internal Med, N-0407 Oslo, Norway
[5] Hosp Buskerud, N-3004 Drammen, Norway
关键词
Aalen's additive model; counting processes; dynamic covariates; event history analysis; multivariate survival data; repeated events; survival analysis;
D O I
10.1111/j.0006-341X.2004.00227.x
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We present an approach for analyzing internal dependencies in counting processes. This covers the case with repeated events on each of a number of individuals, and more generally, the situation where several processes are observed for each individual. We define dynamic covariates, i.e., covariates depending on the past of the processes. The statistical analysis is performed mainly by the nonparametric additive approach. This yields a method for analyzing multivariate survival data, which is an alternative to the frailty approach. We present cumulative regression plots, statistical tests, residual plots, and a hat matrix,plot for studying outliers. A program in R and S-PLUS for analyzing survival data with the additive regression model is available on the web site www.med.uio.no/imb/stat/addreg. The program has been developed to fit the counting process framework.
引用
收藏
页码:764 / 773
页数:10
相关论文
共 24 条
[1]   NONPARAMETRIC INFERENCE FOR A FAMILY OF COUNTING PROCESSES [J].
AALEN, O .
ANNALS OF STATISTICS, 1978, 6 (04) :701-726
[2]   A LINEAR-REGRESSION MODEL FOR THE ANALYSIS OF LIFE TIMES [J].
AALEN, OO .
STATISTICS IN MEDICINE, 1989, 8 (08) :907-925
[3]   ANALYSIS OF DEPENDENT SURVIVAL-DATA APPLIED TO LIFETIMES OF AMALGAM FILLINGS [J].
AALEN, OO ;
BJERTNESS, E ;
SONJU, T .
STATISTICS IN MEDICINE, 1995, 14 (16) :1819-1829
[4]   STATISTICAL-ANALYSIS OF REPEATED EVENTS FORMING RENEWAL PROCESSES [J].
AALEN, OO ;
HUSEBYE, E .
STATISTICS IN MEDICINE, 1991, 10 (08) :1227-1240
[5]   FURTHER RESULTS ON THE NONPARAMETRIC LINEAR-REGRESSION MODEL IN SURVIVAL ANALYSIS [J].
AALEN, OO .
STATISTICS IN MEDICINE, 1993, 12 (17) :1569-1588
[6]  
AALEN OO, 1988, MATH SCI, V13, P90
[7]  
Andersen P. K., 2012, Statistical models based on counting processes
[8]   COX REGRESSION-MODEL FOR COUNTING-PROCESSES - A LARGE SAMPLE STUDY [J].
ANDERSEN, PK ;
GILL, RD .
ANNALS OF STATISTICS, 1982, 10 (04) :1100-1120
[9]  
Cox D., 1972, Stochastic Point Processes. The statistical analysis of dependencies in point processes, P55
[10]  
COX DR, 1972, J R STAT SOC B, V34, P187