Paracoccidioidomycosis: Case report and review

被引:43
作者
Manns, BJ [1 ]
Baylis, BW [1 ]
Urbanski, SJ [1 ]
Gibb, AP [1 ]
Rabin, HR [1 ]
机构
[1] UNIV CALGARY,CTR HLTH SCI,CALGARY,AB T2N 4N1,CANADA
关键词
D O I
10.1093/clinids/23.5.1026
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A previously well 59-year-old man presented with paracoccidioidomycosis, more than 15 years after leaving South America. He failed to respond to conventional therapies, first with oral itraconazole and then with amphotericin B plus sulfadiazine, and eventually died of recurrent arterial emboli possibly due to paracoccidioidomycotic aortitis. This patient's presentation demonstrates the difficulties that may be encountered in diagnosing and managing this disease. Paracoccidioidomycosis should be suspected in patients with an appropriate travel history who experience weight loss and have pulmonary, mucosal, and cutaneous lesions, This article comprehensively reviews the literature, with emphasis on epidemiology, clinical presentation, diagnosis, and therapy with imidazole antifungal medications.
引用
收藏
页码:1026 / 1032
页数:7
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