The great escape - AIDS viruses and immune control

被引：57

作者：

Goulder, PJR

Walker, BD

机构：

[1] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Charlestown, MA 02120 USA

[2] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Charlestown, MA 02129 USA

来源：

NATURE MEDICINE | 1999年 / 5卷 / 11期

关键词：

D O I：

10.1038/15184

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many studies have been designed to address the role of CTL immune escape in HIV-1 infection, but have not given conclusive answers. Now, an elegant longitudinal analysis clearly demonstrates that progression to disease in SIV-infected macaques is associated with evasion of the CTL response (pages 1270–1276).

引用

页码：1233 / 1235

页数：3

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