Epithelial stem cells: Stepping out of their niche

被引：36

作者：

Christiano, AM

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Dermatol, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Dept Genet & Dev, New York, NY 10032 USA

来源：

CELL | 2004年 / 118卷 / 05期

关键词：

D O I：

10.1016/j.cell.2004.08.024

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue of Cell, Blanpain et al. (2004) have shown that two subpopulations of cells exist within the hair follicle stem cell niche. Despite being partially differentiated, clonal populations of suprabasal bulge region cells can regenerate skin and hair follicles as well as a new stem cell niche. The findings suggest that early lineage commitments of epithelial cells in the hair follicle may be reversible.

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收藏

页码：530 / 532

页数：3

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