Synthesis of the C(1)-C(9) segment of the cytotoxic macrolides epothilon A and B

被引：54

作者：

Mulzer, J

Mantoulidis, A

机构：

[1] Inst. fur Org. Chem. der Johann W., D-60439 Frankfurt/Main

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(96)02156-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C(1)-C(9) segment 3 of the macrolides epothilon A and B 1, two new cytotoxic natural products, has been synthesized in a direct manner. Key steps in the synthesis are a stereoselective aldol reaction of 6 and 7 and a Brown allylation of 9. Copyright (C) 1996 Published by Elsevier Science Ltd

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页码：9179 / 9182

页数：4

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