The International Society of Pediatric and Adolescent Diabetes guidelines for management of diabetic ketoacidosis: do the guidelines need to be modified?

被引：38

作者：

Wolfsdorf, Joseph I. ^{[1
,2
]}

机构：

[1] Boston Childrens Hosp, Div Endocrinol, Diabet Program, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA

来源：

PEDIATRIC DIABETES | 2014年 / 15卷 / 04期

关键词：

diabetes; diabetic ketoacidosis; management guidelines; INTRAVENOUS INSULIN INFUSION; SUBCLINICAL CEREBRAL EDEMA; RISK-FACTORS; BRAIN HERNIATION; INTRAMUSCULAR INSULIN; BETA-HYDROXYBUTYRATE; CONSENSUS STATEMENT; 0.1; UNITS/KG/H; CHILDREN; THERAPY;

D O I：

10.1111/pedi.12154

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The current version of the International Society of Pediatric and Adolescent Diabetes (ISPAD) guidelines for management of diabetic ketoacidosis (DKA) is largely based on the Lawson Wilkins Pediatric Endocrine Society/European Society of Pediatric Endocrinology (LWPES/ESPE) consensus statement on DKA in children and adolescents published in 2004. This article critically reviews and presents the most pertinent new data published in the past decade, which have implications for diagnosis and management. Four elements of the guidelines warrant modification: (i) The definition of DKA; (ii) insulin therapy; (iii) water and salt replacement; and (iv) blood ss-hydroxybutyrate measurements for the management of DKA.

引用

页码：277 / 286

页数：10

共 61 条

[1]

Insulin infused at 0.05 versus 0.1 units/kg/hr in children admitted to intensive care with diabetic ketoacidosis [J].