Nicorandil associated anal ulceration

被引：70

作者：

Watson, A ^{[1
]}

Al Ozairi, O

Fraser, A

Loudon, M

O'Kelly, T

机构：

[1] Aberdeen Royal Infirm, Dept Gastroenterol, Aberdeen AB25 2ZD, Scotland

[2] Aberdeen Royal Infirm, Dept Surg, Aberdeen AB25 2ZD, Scotland

来源：

LANCET | 2002年 / 360卷 / 9332期

关键词：

D O I：

10.1016/S0140-6736(02)09710-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nicorandil is a vasodilator used to control angina. It has been associated with oral ulceration and stomatitis that resolves upon withdrawal of the drug. We report a series of five patients with non-specific anal ulceration, all of whom received nicorandil for symptomatic control of ischaemic heart disease. Histological appearances were similar and the ulcers healed on withdrawal of the drug. Our results suggest that nicorandil might be a cause of anal ulceration.

引用

页码：546 / 547

页数：2