dictyBase, the model organism database for Dictyostelium discoideum

被引:91
作者
Chisholm, Rex L. [1 ]
Gaudet, Pascale [1 ]
Just, Eric M. [1 ]
Pilcher, Karen E. [1 ]
Fey, Petra [1 ]
Merchant, Sohel N. [1 ]
Kibbe, Warren A. [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Ctr Med Genet, DictyBase, Chicago, IL 60611 USA
关键词
D O I
10.1093/nar/gkj090
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
dictyBase (http://dictybase.org) is the model organism database (MOD) for the social amoeba Dictyostelium discoideum. The unique biology and phylogenetic position of Dictyostelium offer a great opportunity to gain knowledge of processes not characterized in other organisms. The recent completion of the 34 MB genome sequence, together with the sizable scientific literature using Dictyostelium as a research organism, provided the necessary tools to create a well-annotated genome. dictyBase has lever-aged software developed by the Saccharomyces Genome Database and the Generic Model Organism Database project. This has reduced the time required to develop a full-featured MOD and greatly facilitated our ability to focus on annotation and providing new functionality. We hope that manual curation of the Dictyostelium genome will facilitate the annotation of other genomes.
引用
收藏
页码:D423 / D427
页数:5
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