The Ca/P range of nanoapatitic calcium phosphate cements

被引：103

作者：

Driessens, FCM

Boltong, MG

de Maeyer, EAP

Wenz, R

Nies, B

Planell, JA

机构：

[1] Univ Nijmegen, NL-6109 AH Ohe Laak, Netherlands

[2] Calcio BV, NL-6109 AH Ohe Laak, Netherlands

[3] State Univ Ghent, Dept Dent Mat Sci, Ghent, Belgium

[4] Merck Biomat GmbH, D-64271 Darmstadt, Germany

[5] Univ Politecn Catalunya, Dept Met & Mat, Barcelona, Spain

来源：

BIOMATERIALS | 2002年 / 23卷 / 19期

关键词：

calcium phosphate cement; potassium containing apatite; calcium deficient hydroxyapatite; calcium potassium phosphate; calcium potassium sodium phosphate;

D O I：

10.1016/S0142-9612(02)00151-5

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

Nanoapatites are apatites consisting of nanometer size crystals. The commercial calcium phosphate cements set by the precipitation of nanoapatitic calcium phosphates in the range 1.5 less than or equal to Ca/P < 1.8 In this study it is shown that a continuum of nanoapatites can precipitate in the range 0.8 < Ca/P less than or equal to 1.5. In order to be formed these nanoapatites need to incorporate K+ ions. In addition they can incorporate some Na+ ions. Upon immersion in aqueous solutions these nanoapatites loose phosphate, K+ and Na+ so that in an open system they are transformed into calcium deficient hydroxyapatite Ca-9(HPO4)(PO4)(5)OH within about 2 months. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：4011 / 4017

页数：7

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