Synthesis of putative Delta(6)-, Delta(12)- and Delta(15)-desaturase inhibitors

被引：6

作者：

AlDulayymi, JR ^{[1
]}

Baird, MS ^{[1
]}

Dale, CM ^{[1
]}

Grehan, BJ ^{[1
]}

Shortt, MF ^{[1
]}

机构：

[1] UNIV COLL N WALES,DEPT CHEM,BANGOR LL57 2UW,GWYNEDD,WALES

来源：

TETRAHEDRON | 1997年 / 53卷 / 03期

关键词：

D O I：

10.1016/S0040-4020(96)01033-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclopropene fatty acid esters (5) and (6) and (7) have been synthesised as potential structure-based inhibitors of Delta(6)-, Delta(12)- and Delta(15)-desaturases Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1099 / 1110

页数：12

共 55 条

[1]

ALDULAYYMI J, UNPUB

[2]

ALDULAYYMI JR, 1996, TETRAHEDRON, V38, P12509

[3]

ANDIRANAIVOFEHI.AA, 1993, BIOCHIM BIOPHYS ACTA, P1210

[4]

ANDO T, 1995, J PESTIC SCI, V20, P25

[5]

ANDRIANAIVORAFEHIVOLA AA, 1994, REV FR CORPS GRAS, V41, P53

[6]

ANDRIANAIVORAFEHIVOLA AA, 1994, OLEAGINEUX, V49, P177

[7] MODIFICATIONS OF HEPATIC DRUG-METABOLIZING ENZYME-ACTIVITIES IN RATS FED BAOBAB SEED OIL CONTAINING CYCLOPROPENOID FATTY-ACIDS [J].

ANDRIANAIVORAFEHIVOLA, AA ;

SIESS, MH ;

GAYDOU, EM .

FOOD AND CHEMICAL TOXICOLOGY, 1995, 33 (05) :377-382

[8] SYNTHESIS OF INHIBITORS OF A DELTA-11 DESATURASE IN THE MOTH SPODOPTERA-LITTORALIS [J].

ARSEQUELL, G ;

FABRIAS, G ;

GOSALBO, L ;

CAMPS, F .

CHEMISTRY AND PHYSICS OF LIPIDS, 1992, 63 (1-2) :149-158

[9] INHIBITION OF A DELTA-11 DESATURASE IN SPODOPTERA-LITTORALIS BY 12,13-METHYLENEHEXADEC-12-ENOIC ACID [J].

ARSEQUELL, G ;

FABRIAS, G ;

CAMPS, F .

INSECT BIOCHEMISTRY, 1989, 19 (07) :623-627

[10] A NEW APPROACH TO CYCLOPROPENE FATTY-ACIDS INVOLVING 1,2-DEIODINATION [J].

BAIRD, MS ;

GREHAN, B .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, (14) :1547-1548

← 1 2 3 4 5 6 →