Efficient synthesis of dendrimers via a thiol-yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs

被引：111

作者：

Chen, Gaojian ^{[1
]}

Kumar, Jatin ^{[1
]}

Gregory, Andrew ^{[1
]}

Stenzel, Martina H. ^{[1
]}

机构：

[1] Univ New S Wales, Sch Chem Sci & Engn, CAMD, Sydney, NSW 2052, Australia

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 41期

基金：

澳大利亚研究理事会;

关键词：

CLICK CHEMISTRY; DENDRITIC MACROMOLECULES; BIFUNCTIONAL DENDRIMERS; ADDITION POLYMERIZATION; CONVERGENT SYNTHESIS; ORTHOGONAL SYNTHESIS; MATERIALS SCIENCE; POLYMERS; 1,4-DIETHYNYLBENZENE; FUNCTIONALIZATION;

D O I：

10.1039/b910340f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A combination of thiol-yne chemistry and esterification reactions were successfully applied for the preparation of dendrimers with an array of terminal functionalities via the divergent growth strategy; maximizing the number of reactive chain ends whilst minimizing the number of reaction steps required in the process.

引用

页码：6291 / 6293

页数：3

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