Spatio-temporal dynamics of blood coagulation and pattern formation. An experimental study

被引：11

作者：

Ataullakhanov, FI ^{[1
]}

Krasotkina, YV ^{[1
]}

Sarbash, VI ^{[1
]}

Volkova, RI ^{[1
]}

Sinauridse, EI ^{[1
]}

Kondratovich, AY ^{[1
]}

机构：

[1] Natl Res Ctr Hematol, Moscow 125167, Russia

来源：

INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS | 2002年 / 12卷 / 09期

关键词：

autowave; excitable medium; blood coagulation;

D O I：

10.1142/S0218127402005637

中图分类号：

O1 [数学];

学科分类号：

0701 ; 070101 ;

摘要：

We examined the dynamics of clot growth in vitro and found, that initially the clot grows at a constant speed, then abruptly stops and becomes surrounded by an "inhibition zone" in which coagulation is strongly suppressed. We also observed formation of "stratified structures" (target patterns) in which solid layers alternate with liquid blood. The experimental results strongly support a hypothesis that blood is a new type of excitable medium.

引用

页码：1969 / 1983

页数：15

共 32 条

[1] Ataullakhanov F. I., 1994, Biophysics (English Translation of Biofizika), V39, P99
[2] Ataullakhanov F. I., 1994, Biophysics (English Translation of Biofizika), V39, P91
[3] Spatiotemporal dynamics of clotting and pattern formation in human blood
Ataullakhanov, FI
Guria, GT
Sarbash, VI
Volkova, RI
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1998, 1425 (03): : 453 - 468
[4] CALCIUM THRESHOLD IN HUMAN PLASMA CLOTTING KINETICS
ATAULLAKHANOV, FI
POHILKO, AV
SINAURIDZE, EI
VOLKOVA, RI
[J]. THROMBOSIS RESEARCH, 1994, 75 (04) : 383 - 394
[5] Berliner L.J., 1992, THROMBIN STRUCTURE F
[6] BRUNNEE T, 1993, BLOOD, V81, P580
[7] Colman RW, 1996, BLOOD, V87, P2089
[8] COLMAN RW, 1993, HEMOSTASIS THROMBOSI
[9] THE COAGULATION CASCADE - INITIATION, MAINTENANCE, AND REGULATION
DAVIE, EW
FUJIKAWA, K
KISIEL, W
[J]. BIOCHEMISTRY, 1991, 30 (43) : 10363 - 10370
[10] ESMON CT, 1989, J BIOL CHEM, V264, P4743

← 1 2 3 4 →