Myc in model organisms: A view from the flyroom

被引：37

作者：

de la Cova, Claire ^{[1
]}

Johnston, Laura A. ^{[1
]}

机构：

[1] Columbia Univ, Med Ctr, Dept Genet & Dev, New York, NY 10032 USA

来源：

SEMINARS IN CANCER BIOLOGY | 2006年 / 16卷 / 04期

关键词：

Myc; growth; cell division; ribosome biogenesis; cell competition;

D O I：

10.1016/j.semcancer.2006.07.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The Myc transcription factor regulates fundamental processes in a cell's life: its growth, division, and survival. Myc is conserved throughout metazoan phyla, and its identification in the fruit fly, Drosophila melanogaster has led to new insights in Myc's physiological roles. In this review, we describe recent research on the biology of Myc and its family members in Drosophila, paying particular attention to its role in the control of growth during development. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：303 / 312

页数：10

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