Silicon analogues of the musk odorant versalide

被引：33

作者：

Buettner, Matthias W.

Penka, Martin

Doszczak, Leszek

Kraft, Philip

Tacke, Reinhold

机构：

[1] Univ Wurzburg, Inst Anorgan Chem, D-97074 Wurzburg, Germany

[2] Givaudan Schweiz AG, Fragrance Res, CH-8600 Dubendorf, Switzerland

来源：

ORGANOMETALLICS | 2007年 / 26卷 / 05期

关键词：

D O I：

10.1021/om060934h

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Twofold sila-substitution (C/Si exchange) of the musk odorant Versalide (1a) provides Disila-versalide (1b). The silicon compound 1b and its derivatives 2b (Et/Me exchange) and 3b (Et/H exchange) were synthesized by starting from 1,2-bis(ethynyldimethylsilyl)ethane. The silicon compounds 1b-3b and their carbon analogues 1a-3a were studied for their olfactory properties and their biodegradability.

引用

页码：1295 / 1298

页数：4

共 20 条

[1]

BERSUKER IB, 1991, NEW J CHEM, V15, P307

[2]

CARPENTER MS, 1955, P SCI SECT TOILET GO, V23, P1

[3]

CLASSEN R, 1958, PARFUM KOSMET, V39, P270

[4] CONFORMATIONAL EFFECTS ON RETINOID RECEPTOR SELECTIVITY .2. EFFECTS OF RETINOID BRIDGING GROUP ON RETINOID-X-RECEPTOR ACTIVITY AND SELECTIVITY [J].

DAWSON, MI ;

JONG, L ;

HOBBS, PD ;

CAMERON, JF ;

CHAO, WR ;

PFAHL, M ;

LEE, MO ;

SHROOT, B ;

PFAHL, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (17) :3368-3383

[5]

Doszczak L., 2005, PERSPECTIVES FLAVOR, P89

[6]

GIVAUDAN L, 1956, Patent No. 760667

[7] RETINOBENZOIC ACIDS .1. STRUCTURE-ACTIVITY-RELATIONSHIPS OF AROMATIC AMIDES WITH RETINOIDAL ACTIVITY [J].

KAGECHIKA, H ;

KAWACHI, E ;

HASHIMOTO, Y ;

HIMI, T ;

SHUDO, K .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (11) :2182-2192

[8]

Kraft P, 2005, CHEMISTRY AND TECHNOLOGY OF FLAVORS AND FRAGRANCES, P143

[9]

Kraft P., 2005, PERSPECTIVES FLAVOR, P127

[10]

OPDYKE DLJ, 1979, FOOD COSMET TOXICOL, V17, P241, DOI 10.1016/0015-6264(79)90288-8

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