1,1'-dicyano-2-substituted ethylenes: A new class of glucose uptake inhibitors in antifilarial chemotherapy

被引：8

作者：

Tewari, S

Chauhan, PMS

Bhaduri, AP

Singh, SN

Fatma, N

Chatterjee, RK

Srivastava, VML

机构：

[1] CENT DRUG RES INST,DIV PARASITOL,LUCKNOW 226001,UTTAR PRADESH,INDIA

[2] CENT DRUG RES INST,DIV BIOCHEM,LUCKNOW 226001,UTTAR PRADESH,INDIA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(97)00322-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Several 1,1'-dicyano-2-substituted ethylenes (2-16) were synthesized and evaluated for in vivo antifilarial activity. Some of the screened compounds showed significant antifilarial response against Acanthocheilonema viteae in rodents. (C) 1997 Elsevier Science Ltd.

引用

页码：1891 / 1896

页数：6

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