Hypoxia and HIF-1α stability -: Another stress-sensing mechanism for Shc

被引:6
作者
Abe, J [1 ]
Berk, BC [1 ]
机构
[1] Univ Rochester, Ctr Cardiovasc Res, Rochester, NY USA
关键词
signal transduction; Shc; hypoxia-inducible factor-1; hypoxia;
D O I
10.1161/01.RES.0000026654.65882.55
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:4 / 6
页数:3
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共 23 条
  • [1] Stabilization of wild-type p53 by hypoxia-inducible factor 1α
    An, WG
    Kanekal, M
    Simon, MC
    Maltepe, E
    Blagosklonny, MV
    Neckers, LM
    [J]. NATURE, 1998, 392 (6674) : 405 - 408
  • [2] Role of HIF-1α or in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    Carmeliet, P
    Dor, Y
    Herbert, JM
    Fukumura, D
    Brusselmans, K
    Dewerchin, M
    Neeman, M
    Bono, F
    Abramovitch, R
    Maxwell, P
    Koch, CJ
    Ratcliffe, P
    Moons, L
    Jain, RK
    Collen, D
    Keshet, E
    [J]. NATURE, 1998, 394 (6692) : 485 - 490
  • [3] ASSOCIATION OF SOS RAS EXCHANGE PROTEIN WITH GRB2 IS IMPLICATED IN TYROSINE KINASE SIGNAL TRANSDUCTION AND TRANSFORMATION
    EGAN, SE
    GIDDINGS, BW
    BROOKS, MW
    BUDAY, L
    SIZELAND, AM
    WEINBERG, RA
    [J]. NATURE, 1993, 363 (6424) : 45 - 51
  • [4] Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation
    Gotoh, N
    Toyoda, M
    Shibuya, M
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (04) : 1824 - 1831
  • [5] Shc and FAK differentially regulate cell motility and directionality modulated by PTEN
    Gu, JG
    Tamura, M
    Pankov, R
    Danen, EHJ
    Takino, T
    Matsumoto, K
    Yamada, KM
    [J]. JOURNAL OF CELL BIOLOGY, 1999, 146 (02) : 389 - 403
  • [6] Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor β receptor -: Key role for the p66 adaptor protein Shc
    Heeneman, S
    Haendeler, J
    Saito, Y
    Ishida, M
    Berk, BC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (21) : 15926 - 15932
  • [7] Ishihara H, 1997, J BIOL CHEM, V272, P9581
  • [8] Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α
    Iyer, NV
    Kotch, LE
    Agani, F
    Leung, SW
    Laughner, E
    Wenger, RH
    Gassmann, M
    Gearhart, JD
    Lawler, AM
    Yu, AY
    Semenza, GL
    [J]. GENES & DEVELOPMENT, 1998, 12 (02) : 149 - 162
  • [9] Hypoxic induction of the hypoxia-inducible factor is mediated via the adaptor protein Shc in endothelial cells
    Jung, F
    Haendeler, J
    Hoffmann, J
    Reissner, A
    Dernbach, E
    Zeiher, AM
    Dimmeler, S
    [J]. CIRCULATION RESEARCH, 2002, 91 (01) : 38 - 45
  • [10] Lotti LV, 1996, MOL CELL BIOL, V16, P1946