The taxanes: an update

被引：328

作者：

Crown, J ^{[1
]}

O'Leary, M ^{[1
]}

机构：

[1] St Vincents Univ Hosp, Dublin 4, Ireland

来源：

LANCET | 2000年 / 355卷 / 9210期

关键词：

D O I：

10.1016/S0140-6736(00)02074-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The taxanes are anticancer cytotoxics that stabilise cellular microtubules. Two members, paclitaxel and docetaxel have substantial activity. One or both agents are widely accepted as evidence-based components of therapy for advanced breast, lung, and ovarian carcinomas. Paclitaxel has recently been approved in the USA for the adjuvant treatment of early stage node-positive breast carcinoma.

引用

页码：1176 / 1178

页数：3

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