Macroion-induced compositional instability of binary fluid membranes

被引:43
作者
May, S
Harries, D
Ben-Shaul, A
机构
[1] Univ Jena, Inst Mol Biol, D-07745 Jena, Germany
[2] Hebrew Univ Jerusalem, Dept Phys Chem, IL-91904 Jerusalem, Israel
[3] Hebrew Univ Jerusalem, Fritz Haber Ctr, IL-91904 Jerusalem, Israel
关键词
D O I
10.1103/PhysRevLett.89.268102
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Macroion adsorption on a mixed, fluid, lipid membrane containing oppositely charged lipids induces local changes in lipid composition at the interaction zones, and gradients at their boundaries. Including these effects in the free energy of the macroion-dressed membrane we derive its spinodal equation, and show that nonideal lipid mixing can lead to (lipid-mediated) attraction between macroions and lateral phase separation in the composite membrane. The critical nonideality for this transition is substantially smaller than that of the bare lipid membrane, decreasing with macroion size and charge. That is, the lipid membrane is destabilized by macroion adsorption.
引用
收藏
页码:1 / 268102
页数:4
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