Evaluation of the antiinflammatory hepatoprotective and antioxidant activities of Lycium chinense from Taiwan

被引：21

作者：

Lin, CC

Chuang, SC

Lin, JM

Yang, JJ

机构：

[1] NATL RES INST CHINESE MED,TAIPEI,TAIWAN

[2] ZIEL ENTERPRISE CO,KAOHSIUNG,TAIWAN

[3] KAOHSIUNG MED COLL,SCH PHARM,KAOHSIUNG,TAIWAN

来源：

PHYTOMEDICINE | 1997年 / 4卷 / 03期

关键词：

Lycium chinense; anti-inflammatory; hepatoprotection; free radical; antioxidant activity; electron spin resonance (ESR); LIPID-PEROXIDATION; FOLK MEDICINE; VITAMIN-E; CYTOCHROME-P-450; INJURY; RATS;

D O I：

10.1016/S0944-7113(97)80070-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The relationship between pharmacological and antioxidant activity of the roots, aerial parts and fruits gathered from Lycium chinense were investigated in this study. The extracts of L. chinense showed anti-inflammatory activity against carrageenan induced rat paw edema and CCl4-induced liver injury. Lycium chinense also exhibited antioxidant effects in FeCl2-ascorbic acid-induced lipid peroxidation in rat liver homogenates. Moreover, the free radical scavenger effect of L. chinense was demonstrated using electron spin resonance (ESR) and a spin-trapping technique. Based on these findings, the pharmacological of L. chinense possibly involves mechanisms related to free radical scavenger activity.

引用

页码：213 / 220

页数：8

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