C-reactive protein and atrial fibrillation - Is inflammation a consequence or a cause of atrial fibrillation?

被引：122

作者：

Sata, N

Hamada, N

Horinouchi, T

Amitani, S

Yamashita, T

Moriyama, Y

Miyahara, K

机构：

[1] Shinkyo Hosp, Div Cardiol, Kagoshima 8900073, Japan

[2] Shinkyo Hosp, Div Cardiovasc Surg, Kagoshima 8900073, Japan

来源：

JAPANESE HEART JOURNAL | 2004年 / 45卷 / 03期

关键词：

high-sensitivity C-reactive protein; atrial fibrillation; inflammation;

D O I：

10.1536/jhj.45.441

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To clarify whether inflammation is a cause or consequence of atrial fibrillation (AF), we measured high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-alpha) before and after pharmacological cardioversion in 15 patients with paroxysmal AF. Levels of hs-CRP, IL-6, and TNF-a after cardioversion were significantly higher than those in controls (P < 0.05). Furthermore, the levels of these indices did not differ significantly even at 24 hours and 2 weeks after cardioversion. These results suggest that inflammation is a causative agent of paroxymal AF.

引用

页码：441 / 445

页数：5

共 6 条

[1] C-reactive protein elevation in patients with atrial arrhythmias - Inflammatory mechanisms and persistence of atrial fibrillation [J].